3,3'-(Propane-2,2-diylbis(sulfanediyl))dipropionic acid 是一种ROS敏感性可降解linker，广泛应用于ADC合成。该化合物有潜力在肿瘤药物递送系统的研究中发挥作用。

Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria[1].

Hydroxy-PEG4-acid, a non-cleavable 4-unit PEG ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs) [1].

Azido-PEG6-NHS ester is a cleavable 6 unit polyethylene glycol (PEG) linker, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, it serves as a PEG- and alkyl/ether based linker for the synthesis of proteolysis targeting chimeras (PROTACs)[2].

N3-PEG4-C2-Pfp ester is a four-unit polyethylene glycol linker, noncleavable in nature, specifically employed in the fabrication of antibody-drug conjugates (ADCs).

Fmoc-N-methyl-PEG3-CH2CH2COOH is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1].

(2-Pyridyldithio)-PEG1-hydrazine is a one-unit cleavable polyethylene glycol (PEG) linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This linker offers the advantage of controlled release of the drug payload from the ADC construct. It is utilized in the conjugation process between the antibody and the cytotoxic drug, enabling the targeted delivery of the drug to cancer cells. The (2-pyridyldithio) group of this linker provides stability during circulation in the bloodstream, while the hydrazine moiety allows for efficient drug release at the tumor site. Overall, the (2-pyridyldithio)-PEG1-hydrazine linker serves as a valuable tool in the development of targeted chemotherapeutic agents for cancer treatment.

m-PEG11-acid is a non-cleavable 11-unit polyethylene glycol (PEG) linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1]. It is similarly employed as a PEG-based linker for PROTAC synthesis [2].

Mal-PEG2-Val-Cit-amido-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).