SC-26196 是一种 Delta6 去饱和酶 (D6D, FADS2) 抑制剂 (在大鼠肝微粒体中，IC50=0.2 µM)，具有口服活性，具有抗炎作用。

Xanthine oxidase (XO) 是负责嘌呤分解代谢并转化为尿酸的酶，可产生活性氧，可用于研究心血管疾病。

ALR2-IN-10 (Compound 23) 是一种对醛糖还原酶 2 (Aldose Reductase 2) 具有低效抑制作用的化合物，抑制率在 27μM 浓度下为 6%。ALR2-IN-10 可用于糖尿病并发症研究。

Fluorobexarotene 是一种有效的 类视黄醇 X 受体 (RXR) 激动剂。Fluorobexarotene 对 RXRα 受体的 Ki 值为 12 nM，EC50 值为 43 nM。Fluorobexarotene 具有明显的 RXR 结合亲和力，比 Bexarotene 高75%。

RORγt modulator 5 是一种 RORγt 调节剂，Ki 值 <100 nM。RORγt modulator 5 可用于研究 RORy 介导的炎症、代谢、自身免疫和其他疾病。

HX-600 is a synthetic agonist for the RXR-Nurr1 heterodimer complex. HX-600 prevents ischemia-induced neuronal damage.

7β,27-dihydroxy Cholesterol is an oxysterol and agonist of retinoic acid receptor-related orphan receptor γ (RORγ) and RORγt. [1] It activates RORγ- or RORγt-dependent signaling with EC50 values of 691 and 1,045 nM, respectively, in reporter assays using HEK293T cells expressing the recombinant human receptors. 7β,27-dihydroxy Cholesterol is selective for RORγ and RORγt over a panel of eight additional nuclear receptors at 30 µM. It increases IL-17A production in Th17-polarized isolated human na ve CD4+ T cells when used at a concentration of 300 nM. 7β,27-dihydroxy Cholesterol (60 mg/kg) increases IL-17A production in isolated mouse γδ T cells stimulated with 12-myristate 13-acetate and ionomycin .

Heme Oxygenase-1-IN-1 (HO-1-IN-1) 是一种血红素加氧酶 1 (HO-1) 抑制剂，IC50=250 nM。

EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM. EMD638683 R-Form is the R-form of EMD638683.