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D,L-erythro-PDMP
目录号:SY-128934
D,L-erythro-PDMP, an erythro isomer of PDMP, exhibits growth inhibition on cultured rabbit skin fibroblasts. Additionally, this compound serves as an effective inhibitor of UDP-glucose: ceramide glucosyltransferase.
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Andrastin A
目录号:SY-128935
Andrastin A 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125574,CAS号为 174232-42-9。
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D-threo-PPMP hydrochloride
目录号:SY-128936
D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor.1,2It is the active enanantiomer and enzymatic inhibitory component of the racemic DL-threo-PPMP . In MDCK kidney epithelial cells, D-threo-PPMP induces a 70% reduction in cell growthin vitroat 20 μM and significantly inhibits DNA synthesis at 3 μM.3[Matreya, LLC. Catalog No. 1865] 1.Shen, W., Henry, A.G., Paumier, K.L., et al.Inhibition of glucosylceramide synthase stimulates autophagy flux in neuronsJ. Neurochem.129(5)884-894(2014) 2.Lee, L., Abe, A., and Shayman, J.A.Improved inhibitors of glucosylceramide synthaseJ. Biol. Chem.274(21)14662-14669(1999) 3.Abe, A., Inokuchi, J.-i., Jimbo, M., et al.Improved inhibitors of glucosylceramide synthaseJ. Biochem.111(2)191-196(1992)
¥4025.00
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Zaragozic acid A trisodium
目录号:SY-128937
Zaragozic acid A trisodium 是真菌的代谢产物,具有作为角鲨烯合成酶可逆竞争性抑制剂的功能。
¥9120.00
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Miglustat-D9 hydrochloride
目录号:SY-128938
Miglustat-D9 hydrochloride为Miglustat Hydrochloride (TQ0155)的氘代物,属于葡萄糖神经酰胺合成酶抑制剂,主要用于治疗I型戈谢病。
¥3468.00
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SAHO
目录号:SY-128939
SAHO是一种儿茶酚 - O - 甲基转移酶(COMT)抑制剂,其 IC50 数值为 860 μM,可应用于甲基化反应调控剂相关的研究工作。
¥908.00
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Lipiferolide
目录号:SY-128940
Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitory activity against several tumor cells, it possesses cytotoxic activity against KB cells. Liriodenine also has antiplasmodial activity.
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7beta-Methoxyrosmanol
目录号:SY-128941
7beta-Methoxyrosmanol inhibited acyl CoA:diacylglycerol acyltransferase (DGAT)1 activity, with the IC50 values ranging from 39.5 ± 0.6 to 144.2 ± 3.1 μM.
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PG 34
目录号:SY-128942
PG 34 是 OSMI-1 的结构类似物,也是 O-GlcNAc 转移酶 (OGT) 的弱抑制剂,其 IC50 值为 68 μM。
¥570.00
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