DC1SMe

目录号：SY-100616

DC1 is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065. DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer. DC1Sme is a DC1 derivative with IC50 values of Ramos, Namalwa, HL60 / s

¥6900.00

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INX-SM-6

目录号：SY-100617

INX-SM-6适用于靶向输送抗炎药物。它能在PBMCS细胞中抑制LPS引发的IL-1β产生。

¥4370.00

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PBD-monoamide

目录号：SY-100618

PBD-monoamide, a modified pyrrolobenzodiazepine (PBD) dimer, functions as an ADC cytotoxin. It is utilized in synthesizing DHES0815A (an HER2 ADC) and possesses DNA-binding activity that reduces cell viability [1].

¥5221.00

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Glucocorticoid receptor agonist-3

目录号：SY-100619

Glucocorticoid receptoragonist-3 (Preparation 6) 属于糖皮质激素受体激动剂类化合物。

¥2002.00

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Dox-btn2

目录号：SY-100620

Dox-btn2 是 Doxorubicin 的生物素化衍生物，在 3'-NH2 与阿霉素的偶联点上有生物素标记。Dox-btn2 可用于细胞成像。Doxorubicin 主要积累在细胞核中，而 Dox-btn2 主要位于细胞质中。

¥7315.00

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MYX1715

目录号：SY-100621

MYX1715，作为N-肉豆蔻酰转移酶（NMT）的抑制剂，其KD值为0.09 nM。该化合物能有效抑制LU0884和LU2511细胞系的增殖，其IC50分别为44 nM和9 nM。在小鼠模型中，MYX1715对神经母细胞瘤和胃癌展示了显著的抗肿瘤活性，并可作为ADC毒素使用。

¥5348.00

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Glucocorticoid receptor agonist-4

目录号：SY-100622

Glucocorticoid Receptor Agonist-4 (Compound Preparation 5) serves as an agonist for glucocorticoid receptors and can be conjugated with TNF-α antibodies, facilitating research into autoimmune and inflammatory diseases [1].

¥2002.00

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Exatecan Intermediate 7

目录号：SY-100623

Exatecan Intermediate 7 为Exatecan的中间体.Exatecan (DX-8951) 作为一种抑制DNA拓扑异构酶I (topoisomerase I) 的化合物,具有IC50值2.2 μM (0.975 μg/mL),主要用于癌症研究.此中间体还可用于合成抗体-药物偶联物 (Antibody-Drug Conjugates (ADCs)).

¥1840.00

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Duocarmycin DM free base

目录号：SY-100624

Duocarmycin is a DNA minor groove binding alkylating agent and explored as drug–antibody conjugates (ADCs) . Duocarmycin is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity.

¥3335.00

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