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4-Methylumbelliferyl phosphate disodium
目录号:SY-128309
4-Methylumbelliferyl phosphate disodium (4-MUP) 是一种阴离子有机磷酸酯,作为酸性和碱性磷酸酶(phosphatase)的荧光底物,同时也用作神经毒剂模拟剂。
¥550.00
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3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid
目录号:SY-128310
(24E)-3,4-Seco-cucurbita-4,24-diene-3,26,29-trioic acid can inhibit the activity of protein tyrosine phosphatase 1B (PTP1B), with IC 50 values of 0.4uM.
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NCGC00249987
目录号:SY-128311
NCGC00249987 is a highly selective and allosteric Tyr phosphatase activity of inhibitor of Eya2(Eya2 ED and MBP-Eya2 FL with IC50s of 3 μM and 6.9 μM ).
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PTP1B-IN-4
目录号:SY-128312
PTP1B-IN-4 (NUN-17724)是一种 PTP1B 的变构抑制剂,IC50为8μM。PTP1B-IN-4可用于肥胖症和糖尿病的研究。
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SHP2 protein degrader-2
目录号:SY-128313
SHP2protein degrader-2 (SHP2-D26) 是一种SHP2蛋白PROTAC 降解剂。SHP2protein degrader-2 可降低各种癌细胞中SHP2的表达水平。
¥5005.00
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MDK-4823
目录号:SY-128314
MDK-4823, also known as LMPTP inhibitor1, is a potent low-molecular-weight tyrosine phosphatase (LMPTP) inhibitor. LMPTP is highly expressed in insulin-target tissues. LMPTP promotes diabetes and insulin resistance in obesity.
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Hexane-1,6-diol
目录号:SY-128315
Hexane-1,6-diol is a diol commonly employed to dissolve liquid-liquid phase separation precipitates. It impairs kinase and phosphatase activity and partially inhibits DNA polymerase.
¥238.00
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SHP2-IN-13
目录号:SY-128316
SHP2-IN-13是一种针对SHP2“tunnel site” 的变构抑制剂,具备高选择性及口服活性,IC50值为83.0 nM。该化合物可作为研究潜力药物,用于治疗携带RTK致癌驱动因素的癌症以及SHP2相关疾病。
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Neocryptotanshinone II
目录号:SY-128317
Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-κB and iNOS signaling pathways.
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