15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals. 15-keto Latanoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Although much less potent that the parent compound latanoprost, 15-keto latanoprost still retains the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 μg/eye. 15-keto Latanoprost is also a miotic in the normal cat eye, causing an 8 mm Hg reduction in pupillary diameter at 5 μg/eye. Again, this is not as potent as many other F-type prostaglandins; for example, prostaglandin F2α will produce this degree of miosis at a dose of less than 1 μg/eye.

Calcitroic acid 为维生素 D 受体 (VDR) 激动剂，能够激活 VDR 介导的转录。它是 1,25-二羟基维生素 D3 的主要代谢物，在小鼠肝脏和粘膜中浓度最高，具有代谢稳定性和极低毒性。

O-Desmethyl apixaban is a metabolite of Apixaban and a highly selective, reversible inhibitor of Factor Xa, with Ki values of 0.08 nM in humans and 0.17 nM in rabbits.

Pseudoerythromycin A enol ether is a degradation product of erythromycin. It does not possess antibiotic activity and can be used as an analytical standard for erythromycin A stability studies.

Desmethyl Levofloxacin, a metabolite of levofloxacin, is associated with a synthetic fluoroquinolone antibacterial drug that inhibits the super-coiling activity of bacterial DNA gyrase, thereby preventing DNA replication.

3'-Hydroxy Repaglinide, a primary CYP2C8 metabolite of Repaglinide, is derived from carbamoylmethyl benzoic acid and is used in the treatment of type II diabetes.

Chlorthalidoneimpurity，作为Chlorthalidone的代谢物，该物质属于噻嗪类利尿剂，主要用于高血压的研究。

2,3-dinor-8-iso Prostaglandin F1α（2,3-dinor-8-iso PGF1α）是一种异前列腺素和花生四烯酸的活性代谢物，也是血小板聚集抑制剂8-iso PGF2α的产物。它通过花生四烯酸的非酶促自由基过氧化作用形成。2,3-dinor-8-iso PGF1α在孤立的猪视网膜和大脑微血管中引起血管收缩（EC50s分别为12.8和18.5 nM），但在31 µM的浓度下使用时不会引起孤立的大鼠主动脉环的收缩。在1 µM的浓度下使用时，它能增加孤立的猪大脑切片中的血栓素B2（TXB2）水平，这一效应可以通过血栓素A合成酶抑制剂CGS 12970、电压门控钙通道抑制剂SKF 96365或烟碱型乙酰胆碱受体（nAChR）拮抗剂α-conotoxin来逆转。

Hydroxy desmethyl Bosentan (Ro 64-105) is a Bosentan metabolism produced by the cytochrome P450 enzymes CYP2C9 and CYP3A4 in the liver.