trans-Ned 19是一种烟酸腺嘌呤二核苷酸磷酸（NAADP）拮抗剂和双孔通道（TPC）阻断剂，通过高亲和力结合NAADP受体以抑制NAADP依赖性的溶酶体/内溶酶体钙离子释放，且不影响IP3或cADPR介导的钙信号通路。trans-Ned 19在功能上可抑制葡萄糖诱导的胰岛钙振荡及低浓度组胺诱导的内皮依赖性血管舒张，并能减少埃博拉病毒对宿主细胞的感染。在免疫调节方面，trans-Ned 19介导的NAADP信号阻断可促进小鼠Th17细胞向调节性T细胞（Treg）转化，并在肠道炎症模型中显示出保护效应。

L-Phenylalanine-13C6是13C标记的L-Phenylalanine (T3377)。L-Phenylalanine ( (S)-2-Amino-3-phenylpropionic acid)是一种从大肠杆菌中提取的必需氨基酸，它能作为电压依赖性α2δ亚基Ca2+通道拮抗剂，Ki值为980 nM。在NMDARs (KB573 μM)和非NMDARs中，它是甘氨酸和谷氨酸结合位点的竞争性拮抗剂。日常生活中，L-Phenylalanine 广泛应用于食品香料和药品的制造。

Halofuginone hydrochloride (RU-19110)，Febrifugine的衍生物，作为脯氨酰-tRNA合成酶竞争性抑制剂，其Ki值为18.3 nM。该化合物特异性抑制I型胶原合成，并能通过降低TGF-β活性来减轻骨关节炎症状。同时，Halofuginone hydrochloride 作为有效的肺血管扩张剂，通过激活Kv通道并阻断电压门控、受体操作与存储操作的Ca2+通道发挥作用。此外，它还具有抗疟疾、抗炎、抗癌及抗纤维化的多重生物活性。

Budiodarone（ATI-2042）is a chemical analog of an antiarrhythmic drug and amiodarone. Budedalone is promising as an antiarrhythmic agent for the prevention of atrial fibrillation.

Bifemelane 是一种益智化合物， 通过刺激细胞内 Ca2+储存的释放产生第一个峰值，通过储存操作的 Ca2+通道的电容进入产生第二个峰值。Bifemelane 可作为星形胶质细胞基础研究的药理学工具。

Azumolene sodium anhydrous is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum. Azumolene inhibits a component of store-operated calcium entry coupled to the skeletal muscle ryanodine receptor. Azumolene, an equipotent dantrolene analog, inhibits a component of SOCE coupled to activation of RyR1 by caffeine and ryanodine, whereas the SOCE component induced by thapsigargin is not affected.

Selective CaV3.1 channel blocker (IC50 values are 0.2 and 31.8 μM for hCaV3.1 and hCaV3.2 respectively). Also reversibly inhibits NaV1.8 and blocks KV2.1 channels.

O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine is a major metabolite of the calcium channel inhibitor amlodipine .1 1.Taguchi, R., Naito, T., Sato, H., et al.Validated LC-MS/MS method for the simultaneous determination of amlodipine and its major metabolites in human plasma of hypertensive patientsTher. Drug Monit.39(6)625-631(2017)

(R)-Lercanidipine hydrochloride is the R-enantiomer of Lercanidipine. (R)-lercanidipine hydrochloride is a blocker of calcium channel.