RORγt Inverse agonist 10 is a highly potent and orally bioavailable compound that acts as an antagonist for the retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt). With an IC50 of 51 nM, it effectively inhibits the activity of RORγt, a prominent transcription factor involved in the regulation of genes associated with the pathogenesis of psoriasis, including IL-17A, IL-22, and IL-23R.

AC-261066是一种口服的RARβ2的同型选择性激动剂，pEC50为8.0。

16 alpha-Hydroxytrametenolic acid can inhibit 12-O-tetradecanoylphorbol 13-acetate (TAP)-induced mouse ear edema.

BMS270394 是一种 RARγ激动剂，可用于研究乳腺癌和皮肤病。

KCL-286是一种可口服且具有有效性的视黄酸受体β激动剂，可用于改善脊髓损伤(SCI)。

TMP780 is an inverse RORγt agonist (IC50: 13 nM). RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders.

Disufenton sodium (NXY-059) 是一种神经保护剂 phenylbutynitrone 的衍生物，具有强大的自由基清除能力。

ALRT 1550, a retinoic acid agent (RAR) agonist, is used potentially for the treatment of cervical carcinoma.

BMS 753是亚型选择性的视黄酸受体α（RARα，Ki=2nM）的激动剂。