PDE7 inhibitor S14

目录号：SY-128124

PDE7 inhibitor S14 is a cell-permeable PDE7 inhibitor that acts by targeting the cyclic adenosine monophosphate (cAMP)/cAMP-response element-binding protein (CREB) pathway.

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Deltasonamide 2

目录号：SY-128130

Deltasonamide 2 is a competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM.

¥621.00

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FR-229934

目录号：SY-128118

FR-229934 is a bio-active chemical. Detailed information has not been published.

¥552.00

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Sp-cAMPS triethylamine

目录号：SY-128110

Sp-cAMPS triethylamine，一种 cAMP 类似物，是一种依赖 cAMP 的PKAI 和PKAII 的有效激活剂。Sp-cAMPS triethylamine 还是一种有效的竞争性磷酸二酯酶 (PDE3A) 抑制剂，Ki 为 47.6 µM。Sp-cAMPS triethylamine 以EC50为 40 μM 来结合PDE10GAF 域。

¥3312.00

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Kuraridine

目录号：SY-128112

Kuraridine is measured against cGMP PDE5 to identify potent cGMP specific phosphodiesterase type 5 inhibitory constituents.

¥8706.00

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endo CNTinh-03

目录号：SY-128128

Endo CNTinh-03 具有抑制作用，可阻止 cAMP 和 cGMP 通过 G 蛋白偶联受体、腺苷酸环化酶及鸟苷酸环化酶的激动剂而升高（IC50为 4 μM）。此外，该化合物能够抑制霍乱毒素与Escherichia coli(STa) 毒素导致的氯离子电流，有效改善小鼠分泌性腹泻的症状，并在多囊肾病模型中防止囊肿的形成。

¥3450.00

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Obscurolide A1

目录号：SY-128096

Obscurolide A1 是一种可从链霉菌 viridochromogenes 的培养硝酸盐中分离出的丁内酯，对牛的钙/钙调节非依赖性和非依赖性磷酸二酯酶表现出较弱的抑制活性

¥690.00

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Yonkenafil HCl

目录号：SY-128104

Yonkenafil HCl, a PDE5 inhibitor, is used potentially for the treatment of erectile dysfunction.

¥460.00

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CI-1044

目录号：SY-128102

CI-1044 is an inhibitor of PDE4 (IC50s: 0.29, 0.08, 0.56, 0.09 μM for PDE4A5, PDE4B2, PDE4C2 and PDE4D3).

¥3795.00

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