BT317 是一种可穿越血脑屏障的双重抑制剂，可同时抑制线粒体 LonP1 蛋白酶及 CT-L 蛋白酶体活性。BT317 可升高ROS水平、诱导星形胶质瘤细胞凋亡，并具有抗肿瘤作用。

Suc-Ala-Ala-Pro-Phe-SBzl 是一种化合物，可以作为大鼠小肠肥大细胞蛋白酶（RMCP I）、大鼠骨骼肌肥大细胞蛋白酶（RMCP II）和胰凝乳蛋白酶（Chymotrypsin）的底物。此外，Suc-Ala-Ala-Pro-Phe-SBzl 能够被甘氨酸（R208G）水解。

PK44 phosphate 是二肽基肽酶 IV (DPP-IV) 的有效抑制剂 (IC50: 15.8 nM)。

16-Hydroxycleroda-3,13-dien-15,16-olide, and prodigiosin are presented as candidates for autophagy inducers that can trigger cell death in a supplement or alternative medicine for cancer therapy. 16-Hydroxycleroda-3,13-dien-15,16-olide regulates the expre

Enzyme-IN-1（compound 1）为基于肽的N端亲核试剂（Ntn）水解酶抑制剂，特别针对20S蛋白酶体的糜胰蛋白酶样活性（CT-L）进行抑制，可能展现出抗炎特性。

LXE408 is an orally active, kinetoplastid-selective proteasome inhibitor, exhibiting non-competitive inhibitory effects. It demonstrates an IC50 of 0.04 μM for L. donovani proteasome and an EC50 of 0.04 μM for L. donovani. Moreover, LXE408 shows limited ability to traverse the blood-brain barrier. Hence, LXE408 holds promise for advancing research in the field of visceral leishmaniasis (VL).