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SLC7A11-IN-2
目录号:SY-128731
SLC7A11-IN-2 (Compound 1) 是一种有效的SLC7A11/xCT抑制剂,通过下调细胞内谷胱甘肽水平并增加氧化应激来破坏 HeLa 细胞的氧化稳态,从而诱导细胞死亡,其 IC50 值为 10.23 μM。分子动力学模拟表明,该化合物的 SLC7A11 结合能力优于 Erastin。SLC7A11-IN-2 主要应用于宫颈癌的研究领域。
¥1346.00
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Octapeptide-2
目录号:SY-128732
Octapeptide-2, 已报道作为化妆品成分,是一种具促进毛发生长功能的生物活性肽。
¥385.00
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5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate
目录号:SY-128734
5(6)-Carboxy-2’,7’-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.1Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting compound, 5(6)-carboxy-2’,7’,-dichlorofluorescein, is oxidized by reactive oxygen species (ROS) and nitric oxide (NO) and displays excitation/emission maxima of 504 and 530 nm, respectively, which can be quantified as a measure of oxidant production. 1.Hempel, S.L., Buettner, G.R., O’Malley, Y.Q., et al.Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: Comparison with 2’,7’-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2’,7’-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123Free Radic. Biol. Med.27(1-2)146-159(1999)
¥322.00
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CYPMPO
目录号:SY-128735
CYPMPO is a free radical spin trap with excellent trapping capabilities toward hydroxyl and superoxide radicals in biological and chemical systems. Decay of the superoxide adduct of CYPMPO proceeds in an apparent first order fashion with half-lives of 15 and 51 minutes in a UV-illuminated hydrogen peroxide solution and a hypoxanthine/xanthine oxidase system, respectively. CYPMPO traps superoxide radicals generated by bovine neutrophils as effectively as DEPMPO.[1] The high melting point (126°C), low hygroscopic properties, and long shelf-life in aqueous solutions offer significant practical advantages for use of CYPMPO over DEPMPO and DMPO.
¥1852.00
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Polygalacturonic acid
目录号:SY-128736
Polygalacturonic acid(Galacturonic acid polymer)为透明凝胶状聚合物,是植物细胞壁的关键组成成分。Polygalacturonic acid 被用于银纳米颗粒(AgNPs)合成,具有抗氧化与抗炎特性,可保护细胞免受 ROS 诱导的损伤并促进创伤修复。此外,以 Polygalacturonic acid 为载体的纳米颗粒还具有抗菌性能,在生物医学研究及纳米材料开发中具有多功能应用价值。
¥230.00
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(E)-3,4-Dimethoxycinnamic acid
目录号:SY-128737
(E)-3,4-Dimethoxycinnamic acid 是天然化合物 3,4-dimethoxycinnamic acid 的活性较弱的异构体,来源于 Securidaca inappendiculata Hassk。其通过 ROS 介导信号通路在 L-02 细胞中发挥抗凋亡作用,在炎症与免疫研究中具有潜在应用。
¥428.00
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