MK-0941 is an orally active and allosteric glucokinase activator, has potential in the treatment of type 2 diabetes.

Tachioside has antiobesity, antioxidant and α-glucosidase inhibitory activities, it decreases lipid content in 3T3-L1 adipocytes by inhibiting lipogenesis, shows antiobesity activities. Tachioside can inhibit nitric oxide production in lipopolysaccharides-stimulated RAW 264.7 cells with IC50 value of 12.14 μM.

Therapeutic agent-1 (Compound 1a)是一种口服活性的葡萄糖激酶 (GK) 激活剂。它通过增加肝细胞中的葡萄糖磷酸化速率并促进胰岛素分泌，显著降低糖尿病动物模型的空腹血糖水平。

GCase modulator-1是一种有效的变构葡萄糖脑苷脂酶 (GCase) 激活剂。它通过增强溶酶体内 GCase 活性促进底物降解，常用于戈谢病及帕金森病相关的溶酶体功能障碍研究。

Cyclomusalenone is a potent α-glucosidase inhibitor.

Hex 是一种烯醇酶抑制剂与抗疟剂，对 ENO2、ENO1 的 Ki 值分别为 74.4 nM、269.4 nM；对 NfENO、TbENO 的 IC50 分别为 0.14 μM、2.1 μM。Hex 对恶性疟原虫 3D7、福氏耐格里阿米巴滋养体及伯氏疟原虫 ANKA 株均具抗疟活性，同时对颅内肿瘤也表现出一定的抗肿瘤作用。