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Moricizine Hydrochloride
目录号:SY-123720
Moricizine Hydrochloride (EN 313) 是一种口服具有活力的 I 类抗心律失常剂。Moricizine Hydrochloride 能够减少 0 相去极化的速率;提高 2 相和 3 相复极率,降低动作电位持续时间,减少有效不应期。
¥402.00
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(±)17-HETE
目录号:SY-123721
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 μM the (S)-enantiomer of 17-HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R)-isomer is inactive.
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1β-Hydroxydeoxycholic acid
目录号:SY-123722
1β-Hydroxydeoxycholic acid (1β-OH-DCA)为次级胆汁酸,同时作为CYP3A的生物标志物。在使用重组人CYP450酶的过程中,Deoxycholic acid 通过CYP3A4和CYP3A7的特异性代谢转化为1β-Hydroxydeoxycholic acid。
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Testololactone
目录号:SY-123723
Testololactone,一种芳香酶抑制剂,常用于乳腺癌研究。
¥5750.00
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Dihydrocubebin
目录号:SY-123724
Dihydrocubebin,一种从Piper cubeba中分离的化合物,表现出对细胞色素P450 3A4 (CYP3A4) 的有效且选择性抑制。
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(R)-6',7'-Dihydroxybergamottin
目录号:SY-123725
(R)-6',7'-Dihydroxybergamottin is an ihhibitor of CYP1A1 and the isomer of 6',7'-Dihydroxybergamottin(DHB).
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