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Taurolithocholic Acid-D5 Sodium Salt (Major)
目录号:SY-123324
Taurolithocholic Acid-D5 Sodium Salt (Major)是Taurolithocholic Acid Sodium Salt (T4727)的氘代化合物。Taurolithocholic Acid Sodium Salt的CAS号为6042-32-6。Taurolithocholic acid sodium salt是抑胆剂和Ca2+激动剂,可抑制放射性配体与毒蕈碱 M1 结合。
¥4945.00
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8-bromo NAD+ sodium
目录号:SY-123326
8-bromo NAD+ 作为循环ADP-核糖(cADPR)抑制剂8-bromo cADPR的前药形式,通过CD38转化为8-bromo-cADPR。在1 mM浓度下,8-bromo NAD+ 阻止由N-formyl-Met-Leu-Phe (fMLP) 在分离的小鼠骨髓衍生的中性粒细胞内引起的细胞内钙水平增加和趋化作用。同时,在100 µM浓度下使用,减少了小鼠原代小胶质细胞中LPS诱导的亚硝酸盐产生以及TNF-α和IL-2的分泌。
¥1035.00
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(-)-α-Eudesmol
目录号:SY-123328
(-)-α-Eudesmol为一种二萜二醛类化合物,源自Porella。
¥7360.00
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Calcium Channel antagonist 5
目录号:SY-123330
Calcium Channel antagonist5 (compound 32) 是一种钙通道拮抗剂,pIC50为5.50。
¥225.00
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Verapamil EP Impurity C hydrochloride
目录号:SY-123332
NSC-609249 hydrochloride, an impurity of Verapamil, is a calcium channel blocker with potent orally active properties. It also functions as a first-generation P-glycoprotein (P-gp) inhibitor.
¥1155.00
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D-myo-Inositol-1,3-diphosphate (sodium salt)
目录号:SY-123334
D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(1,3)P2 can be dephosphorylated to Ins(1)P by inositol polyphosphate 3-phosphatase and further dephosphorylated to inositol by inositol monophosphatase.
¥6106.00
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