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Budiodarone
目录号:SY-123335
Budiodarone(ATI-2042)is a chemical analog of an antiarrhythmic drug and amiodarone. Budedalone is promising as an antiarrhythmic agent for the prevention of atrial fibrillation.
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Bifemelane
目录号:SY-123337
Bifemelane 是一种益智化合物, 通过刺激细胞内 Ca2+储存的释放产生第一个峰值,通过储存操作的 Ca2+通道的电容进入产生第二个峰值。Bifemelane 可作为星形胶质细胞基础研究的药理学工具。
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Azumolene sodium anhydrous
目录号:SY-123339
Azumolene sodium anhydrous is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum. Azumolene inhibits a component of store-operated calcium entry coupled to the skeletal muscle ryanodine receptor. Azumolene, an equipotent dantrolene analog, inhibits a component of SOCE coupled to activation of RyR1 by caffeine and ryanodine, whereas the SOCE component induced by thapsigargin is not affected.
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ProTx-I
目录号:SY-123341
Selective CaV3.1 channel blocker (IC50 values are 0.2 and 31.8 μM for hCaV3.1 and hCaV3.2 respectively). Also reversibly inhibits NaV1.8 and blocks KV2.1 channels.
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O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine
目录号:SY-123343
O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine is a major metabolite of the calcium channel inhibitor amlodipine .1 1.Taguchi, R., Naito, T., Sato, H., et al.Validated LC-MS/MS method for the simultaneous determination of amlodipine and its major metabolites in human plasma of hypertensive patientsTher. Drug Monit.39(6)625-631(2017)
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(R)-Lercanidipine hydrochloride
目录号:SY-123345
(R)-Lercanidipine hydrochloride is the R-enantiomer of Lercanidipine. (R)-lercanidipine hydrochloride is a blocker of calcium channel.
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