MMAF intermediate 1

目录号：SY-100666

MMAFintermediate 1 用于合成MMAF.MMAF (Monomethylauristatin F) 作为一种有效的微管蛋白聚合抑制剂,广泛应用于抗体偶联药物(ADCs)中,充当细胞毒性成分,例如 Vorsetuzumab mafodotin 和 SGN-CD19A 中的 ADC Cytotoxin.

¥332.00

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Glucocorticoid receptor agonist-5

目录号：SY-100667

Glucocorticoid receptoragonist-5 (compound 4) 作为一种糖皮质激素分子，兼具抗炎和免疫抑制的功能，是一种有效的糖皮质激素受体激动剂。此外，该化合物还被应用作为ADC 细胞毒素。

¥2840.00

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Exatecan Intermediate 1-d5

目录号：SY-100668

Exatecan Intermediate 1-d5为Exatecan Intermediate 1的氘化形式.

¥1518.00

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Maytansinoid B

目录号：SY-100669

Maytansinoid B 是一种ADC Cytotoxin，用于形成与抗体结合的Antibody-Drug Conjugates (ADCs)。它是一种抗有丝分裂剂，能够结合微管蛋白并阻断其组装，诱导细胞周期在G2/M阶段停滞，进而触发细胞凋亡(apoptosis)。

¥2852.00

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Duocarmycin GA

目录号：SY-100670

Duocarmycin GA, an antibody drug conjugate (ADC) toxin and a DNA alkylating agent, effectively targets and binds in the minor groove of DNA. It is particularly potent against multi-drug resistant cell lines, offering a strategic approach in combating resistance.

¥20240.00

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7-MAD-MDCPT

目录号：SY-100671

7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs).

¥2300.00

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