DBCO-β-Glu-PEG12-Exatecan（化合物107）是一种拓扑异构酶I的抑制剂。它可以作为药物-连接子偶联物，用于抗体药物偶联物（ADC）分子的合成。

Puxitatug samrotecan drug-linker (AZD8205 drug-linker)，作为抗B7-H4抗体偶联活性分子 ADC 的关键组成部分 (drug-linker conjugate for ADC)，融合了一个可降解的ADC linker与拓扑异构酶 I 抑制剂Exatecan。

Mal-Phe-C4-VC-PAB-MMAE is a chemical compound resulting from the conjugation of monomethyl auristatin E (MMAE), a potent tubulin inhibitor serving as a toxin payload in antibody-drug conjugates, with a Mal-Phe-C4-VC-PAB linker.

Sulfo-PDBA-DM4 is a drug-linker conjugate for antibody-drug conjugate (ADC) applications, combining the potent tubulin inhibitor DM4 with the gluthatione-cleavable linker Sulfo-PDBA. This configuration harnesses DM4's cytotoxic potential through Sulfo-PDBA's targeted delivery mechanism.

MP-PEG8-VA-PABC-PBD Dimer is a drug-linker conjugates for ADC which is used in the treatment of several cancers. PBD Dimer is a DNA alkylating which inhibits DNA replication[1].

MC-betaglucuronide-MMAE-1 is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADCs), employing MMAE (a tubulin polymerization inhibitor) connected through the cleavable ADC linker MC-betaglucuronide.