Cercosporamide is a ATP-competitive Pkc1 kinase inhibitor (IC50 <50 nM; Ki <7 nM). It also is a unique Mnk inhibitor.

Protein kinase C (PKC) activator

Ruboxistaurin is a PKC beta inhibitor. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/

ζ-Stat trisodium (NSC37044 trisodium) is a potent and selective inhibitor of protein kinase C-ζ (PKC-ζ), exhibiting an IC50 of 5 μM. It effectively suppresses the proliferation of melanoma cell lines and promotes apoptosis. Moreover, ζ-Stat trisodium demonstrates notable antitumor activity in vitro.

FKKSFKL-NH2 是一种蛋白激酶 C 选择性肽。FKKSFKL-NH2 可用于各种生化研究。

C8 Dihydroceramide acts as a negative control for C8 Ceramide, a cell-permeable analog of natural ceramides. C8 Ceramide, also known as N-Octanoyl-D-erythro-sphingosine, exhibits potent chemotherapeutic properties and anti-proliferation effects. Additionally, it stimulates dendritic cells to enhance T cell responses during viral infections. In vitro studies have also shown that C8 Ceramide induces a slight activation of protein kinase (PKC) [4].

AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).

[Ala9,10, Lys11,12] Glycogen Synthase (1-12) 为蛋白激酶 C (PKC) 磷酸化的选择性底物，主要用于测定 PKC 活性。

Myelin Basic Protein (MBP 4-14) 是一种被认为在神经系统神经髓鞘形成过程中起重要作用的蛋白质。