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Coelenterazine
目录号:SY-128545
Coelenterazine 是一种超氧阴离子敏感化学发光探针,可用于检测过氧亚硝酸盐的化学发光,并可以作为 apoaequorin 和 Renilla 荧光素酶的发光酶底物。
¥855.00
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RORγt Inverse agonist 10
目录号:SY-128533
RORγt Inverse agonist 10 is a highly potent and orally bioavailable compound that acts as an antagonist for the retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt). With an IC50 of 51 nM, it effectively inhibits the activity of RORγt, a prominent transcription factor involved in the regulation of genes associated with the pathogenesis of psoriasis, including IL-17A, IL-22, and IL-23R.
¥1694.00
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AGN 193109
目录号:SY-128794
AGN 193109 是一种类视黄醇类似物,是一种有效的特异性 RAR 拮抗剂,可抑制 RARα、RARβ和 RARγ的活性,Kd 值分别为 2 nM、2 nM 和 3 nM。
¥671.00
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RORγt agonist 3
目录号:SY-128537
RORγt agonist 3 是 RORγt 的有效激动剂。RORγt agonist 3 能够促使 Th17 细胞分化,增加促炎细胞因子水平,进而提高淋巴细胞的细胞毒性。RORγt agonist 3 能够阻碍调节性 T 细胞的产生,并免疫反应产生抑制作用。
¥1232.00
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SR1555 HCl
目录号:SY-128542
SR1555 is a selective RORγ inverse agonist that inhibits the development and function of TH17 cells, a subset of T cells that have been involved in the pathology of several autoimmune diseases such as rheumatoid arthritis and multiple sclerosis.
¥1045.00
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Cintirorgon sodium
目录号:SY-128535
Cintirorgon (LYC-55716) is an orally active RORgamma agonist with potential immunomodulatory and antineoplastic activities. LYC-55716 selectively binds to the RORg, and binds to ROR response elements, enhancing the function, proliferation, and survival of
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TMP778
目录号:SY-128532
TMP778 is an effective and selective RORγt inverse agonist (IC50: 7 nM in FRET assay).
¥1584.00
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ALR2-IN-10
目录号:SY-128789
ALR2-IN-10 (Compound 23) 是一种对醛糖还原酶 2 (Aldose Reductase 2) 具有低效抑制作用的化合物,抑制率在 27μM 浓度下为 6%。ALR2-IN-10 可用于糖尿病并发症研究。
¥138.00
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Methyl 13-cis-4-Oxoretinoate
目录号:SY-128795
Methyl 13-cis-4-Oxoretinoate (13-cis-4-Oxo-retinoic acid Methyl Ester) 是神经母细胞瘤中的一种视黄酸代谢物。
¥575.00
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