RORγt Inverse agonist 10 is a highly potent and orally bioavailable compound that acts as an antagonist for the retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt). With an IC50 of 51 nM, it effectively inhibits the activity of RORγt, a prominent transcription factor involved in the regulation of genes associated with the pathogenesis of psoriasis, including IL-17A, IL-22, and IL-23R.

Cremophor EL 是一种非离子表面活性剂。Cremophor EL 抑制细胞代谢，抑制 UGT1A1 介导的大黄素葡萄糖醛酸化。

CORM-401 是一种羰基配合物和一氧化碳释放分子，具有血管生成和抗菌活性。CORM-401 诱导内皮细胞中磷酸戊糖通路的钙信号传导、NO 增加和激活。CORM-401 抑制大肠杆菌和几种抗生素耐药临床病原体的生长，可诱导小鼠体温增加。

4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.

CP-312 (Cardioprotectant 312)是一种抗氧化防御反应激活剂，它通过诱导血红素加氧酶-1发挥作用，通过诱导 HMOX1 表达来靶向抗氧化反应网络，从而保护 hiPSC-CM 的活力。CP-312 保护人 iPSC 衍生的心肌细胞免受氧化应激。

FIPI (5-Fluoro-2-indolyl deschlorohalopemide) 是 halopemide 的衍生物，抑制PLD1和PLD2，IC50值分别为 25 nM 和 20 nM。它防止 PLD 调节 F-肌动蛋白细胞骨架重组、细胞扩散和趋化性。

3'-Hydroxypuerarin 是一种异黄酮，从Pueraria lobata(Willd.) Ohwi 根部分离出来得到。它是抗氧化剂，具有显著的 ONOO(-)，NO•，总 ROS 清除活性。

Calcipotriol monohydrate 是维生素 D3 的类似物，对维生素 D 受体具有高亲和力。Calcipotriol monohydrate 可用于银屑病研究。

AD 0261 is a radical scavenger. It has a strong inhibitory action on the generation of lipid peroxides and superoxide anions.