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ABC47
目录号:SY-128444
ABC47 是一种高效的丝氨酸水解酶 (serine hydrolases) 抑制剂,对ABHD4和ABHD3的IC50分别为0.03 μM和0.1 μM。在研究婴儿神经元蜡样脂褐素沉积症方面,ABC47 发挥了重要作用。
¥2196.00
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Palmostatin B
目录号:SY-128445
Palmostatin B is a modulator of Ras-signaling that acts by targeting acyl protein thioesterase 1 (APT1) and 2 (APT2) in cells.
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1-Aminodecylidene bis-Phosphonic Acid
目录号:SY-128446
1-Aminodecylidenebis-phosphonic acid, with its potent inhibitory effect on acid sphingomyelinase (IC50= 20 nM), shows selectivity by being less effective against neutral sphingomyelinase (IC50= >100 μM). Additionally, it entirely prevents dexamethasone-induced apoptosis in HepG2 cells.
¥2760.00
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LCL521
目录号:SY-128447
LCL521 能抑制溶酶体酸性鞘磷脂酶(ASMase)。LCL521 是一种酸性神经酰胺酶(ACDase)抑制剂。
¥1150.00
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N-Stearoylsphingomyelin
目录号:SY-128448
N-Stearoylsphingomyelin (N-Stearoyl-D-sphingomyelin) 为抑制磷脂酶 Cδ1 (PLCδ1) 的鞘磷脂类化合物。
¥3105.00
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VU0364739
目录号:SY-128449
VU0364739为一种具有选择性的PLD2抑制剂(IC50:22 nM),可降低癌细胞的增殖。
¥2300.00
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CAY10502
目录号:SY-128450
Phospholipase A2 (PLA2) catalyzes the hydrolysis of phospholipids at the sn-2 position leading to the production of lysophospholipids and free fatty acids. Calcium-dependent cytosolic PLA2 (cPLA2α) is a 85 kDa enzyme that plays a key role in the arachidonic cascade and the inflammatory response associated with this metabolic pathway. CAY10502 is a potent inhibitor of calcium-dependent cytosolic PLA2α (cPLA2α) with an IC50 value of 4.3 nM for the purified enzyme from human platelets. It inhibits arachidonic acid mobilization from A23187-stimulated or TPA-stimulated human platelets with IC50 values of 570 and 0.9 nM, respectively.
¥1656.00
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sPLA2 inhibitor 1
目录号:SY-128451
KH064 is a sPLA2-IIA inhibitor of oral activity.
¥6669.00
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SB-435495 hydrochloride
目录号:SY-128452
SB-435495 hydrochloride,一种有效的、选择性的、可逆性非共价口服Lp-PLA2抑制剂,IC50值为0.06 nM。
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