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PF-06471553
目录号:SY-121971
PF-06471553 is an effective and selective inhibitor of monoacylglycerol acyltransferase 3 (IC50: 92 nM).
¥4554.00
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ANAT inhibitor-2
目录号:SY-121972
ANAT inhibitor-2 is a ANAT inhibitor for canavan disease, with an IC 50 value of 20 μM.
¥1552.00
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CAY10486
目录号:SY-121973
Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 μM.
¥874.00
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RP 73163 Racemate
目录号:SY-121974
RP 73163 Racemate is the racemate of RP 73163. RP 73163 is a potent inhibitor of ACAT, shows cholesterol lowering activity.
¥15755.00
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Nevanimibe
目录号:SY-121975
Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).
¥2233.00
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1-Stearoyl-sn-glycerol 3-phosphate sodium
目录号:SY-121976
1-Stearoyl-sn-glycerol 3-phosphate sodium 作为一种功能性磷脂,主要在膜磷脂的合成过程中由多种细胞类型生成,如活化血小板、上皮细胞、白细胞、神经元和肿瘤细胞。这种化合物在血浆中的常见浓度约为100nM,通过与 G 蛋白偶联受体(GPCR)的相互作用,对细胞的活动、增殖、侵袭、生存及生长因子的产生等多个关键生理过程具有调控作用。其分子结构特征为sn-1位置的硬脂酸和sn-2位置的羟基。
¥851.00
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Amidepsine A
目录号:SY-121977
Amidepsine A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T22187,CAS号为 169181-28-6。
¥5348.00
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ApoA-I mimetic peptide
目录号:SY-121978
ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) 显示出高效激活卵磷脂:胆固醇酰基转移酶(LCAT)的功能,适用于合成肽/脂质复合物。
¥747.00
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PF-06424439
目录号:SY-121979
PF-06424439 是一种口服有效的咪唑并吡啶二酰基甘油酰基转移酶 2 (DGAT2)选择性抑制剂,IC50是 14 nM。PF-06424439 具有缓慢可逆的,时间依赖性的特点,其相对于酰基-CoA 底物以非竞争性模式抑制 DGAT2。
¥1438.00
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