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(±)-ε-Viniferin
目录号:SY-123747
(±)-ε-Viniferin,ε-Viniferin的外消旋体,展现P450抑制性抗氧化、保肝及抗菌特性。该化合物对革兰氏阳性菌肺炎链球菌显示出抗菌和抗生物膜活性,最小抑制浓度(MIC)为20 μM。
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Secologanin
目录号:SY-123748
Secologanin is a monoterpene that has been found in V. rosea and is an intermediate in the synthesis of monoterpene indole alkaloids from geraniol.
¥828.00
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Aschantin
目录号:SY-123749
Aschantin 是一种从植物中分离到的木脂素类天然产物。
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(+)-Menthofuran
目录号:SY-123750
(+)-Menthofuran 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125544。
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2-Hydroxy-1-Methoxyaporphine
目录号:SY-123752
2-Hydroxy-1-Methoxyaporphine can inhibit CYP2D6 activity, it also increase the glucose consumption significantly as rosiglitazone.
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CYP19A1/CYP11B2-IN-1
目录号:SY-123753
CYP19A1/CYP11B2-IN-1 是一种高效的芳香化酶(CYP19A1)和醛固酮合酶(CYP11B2)双重抑制剂,其 IC₅₀分别为 2.3 nM 和 29 nM。CYP19A1/CYP11B2-IN-1 可以抑制乳腺癌细胞增殖并促凋亡(对 MCF-7 细胞的 IC₅₀为 0.26 ± 0.03 μM)。CYP19A1/CYP11B2-IN-1 可以通过抑制 mTOR 磷酸化来负调控 PI3K/Akt/mTOR 信号通路。
¥2530.00
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5-methyl Chrysene
目录号:SY-123755
5-Methylchrysene, a carcinogenic polycyclic aromatic hydrocarbon with four fused rings, functions as an aryl hydrocarbon receptor agonist. It is generated through the incomplete combustion of organic matter and primarily detected in gasoline exhaust and tobacco smoke. Additionally, 5-Methylchrysene can be converted into mutagenic metabolites by cytochrome P450 enzymes 1A1 and 1B1.
¥2404.00
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Dehydroindapamide
目录号:SY-123756
Dehydroindapamide 是 Indapamide 的吲哚形式,用作定量分析标准,以测定 CYP3A4 介导的 Indapamide 代谢周转。该化合物表现出约为 Indoline 形式十倍的代谢周转率,并对 CYP3A4 具有略高的亲和力,从而支持药物代谢、酶动力学及药代动力学特征的深入研究。
¥474.00
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(±)11-HETE
目录号:SY-123757
(±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid . The individual R and S isomers of racemic HETEs have been separated and identified using chiral phase HPLC. The racemic HETEs have been quantified as an index of lipid peroxidation using GC/MS.
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