Erb-196 is an estrogen receptor-receptor agonist with non-steroidal selectivity.

Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.

Pure antiestrogen that downregulates estrogen receptor expression

DK1 是有效的雌激素相关受体调节剂。DK1 影响 ERRα 受体的活性，具有降低血糖的能力。DK1 显示出研究糖尿病的潜力。

GNE-502 is an orally active and potent estrogen receptor (ER) degrader, specifically designed for research on breast cancer.

Nitromifene is the estrogen receptor antagonist.

GDC-0927 is a novel,non-steroidal, potent, orally bioavailable, selective estrogen receptor antagonist.

FSHR agonist 1是一种对卵泡刺激素(FSH)受体(FSHR)具有高亲和力并能引起变构的激动剂，具有pEC50值为7.72。它通过与TMD广泛相互作用直接激活FSHR。

Pipendoxifene, also known as ERA-923, is a new antiestrogen with potential anticancer activity. ERA-923 potently inhibits estrogen binding to ER-alpha (IC50 = 14 nM). In ER-alpha-positive human MCF-7 breast carcinoma cells, ERA-923 inhibits estrogen-stimulated growth (IC50 = 0.2 nM) associated with cytostasis. In vitro, a MCF-7 variant with inherent resistance to tamoxifen (10-fold) or 4-OH tamoxifen (>1000-fold) retains complete sensitivity to ERA-923 . In preclinical models, ERA-923 has an improved efficacy and safety compared with tamoxifen. In the combination with temsirolimus, ERA-923 showed excellent anticancer activity in preclinical models.