Toralactone 9-O-triglucoside (Compound 2) 是一种酚类三糖苷，可从决明子中分离。该化合物可用于研究乳腺癌、前列腺癌、骨质疏松症和心血管疾病等与雌激素相关的疾病。

Nafoxidine is a partial estrogen antagonist. It inhibits angiogenesis in some tissues by blocking the effects of VEGF and FGF; paradoxically, it may enhance angiogenesis in uterine tissue. Nafoxidine also induces calcium signaling, oxidative stress, and p

16α-Hydroxy-17β-estradiol-2,4-d2 是 Estriol 的氘代化合物。Estriol 的 CAS 号为 50-27-1。Estriol 是G蛋白偶联雌激素受体拮抗剂，能够作用于雌激素受体阴性乳腺癌细胞。

AZD9496 maleate is a highly potent and selective antagonist of the estrogen receptor alpha (ERα), exhibiting an IC50 value of 0.28 nM. This compound, AZD9496 maleate, is an orally bioavailable selective estrogen receptor degrader (SERD).

agonist at ERα receptor and antagonist at ERβ receptor

Arzoxifene (LY353381) is an orally active selective estrogen receptor modulator (SERM) exhibiting a fixed ring structure analogous to raloxifene. This compound demonstrates potent antiestrogenic effects on breast cancer and endometrium while displaying minimal side effects. Additionally, Arzoxifene elicits favorable estrogenic effects on bone health and lipid profile.

Estrogen receptor-IN-1 (compound 16) 是有效的雌激素受体(ER)抑制剂，其对 ERα 和 Erβ 的IC50值分别为 13 和 5μM。

Arzoxifene hydrochloride is a selective estrogen receptor modulator that is a potent estrogen antagonist in mammary and uterine tissue.

Inokosterone is an analgesic drug. It also shows high insect moulting hormone activity.