Hsp90-IN-37 (Z-2) 是一种热休克蛋白90（Hsp90）抑制剂，对Hsp90酶活性抑制率达到69%，并具有抗肿瘤活性。

KUNB31 is a potent and selective inhibitor of Hsp90β.

MK2-IN-5为Mk2的假底物，Ki值为8 μM。该化合物针对MAPK通路内的蛋白相互作用域，并能抑制HSP25与HSP27的磷酸化。

BF844 is a chemical compound that demonstrates the ability to mitigate hearing loss in individuals with Usher Syndrome Type III (USH3) caused by the CLRN1 mutation (specifically N48K). One of its mechanisms of action is the transportation of CLRN1 N48K to the plasma membrane. In vivo studies have shown that BF844 significantly preserves hearing [1].

4-Br-Bnlm 是葡萄糖调节蛋白 (Grp94) 的选择性抑制剂，EC50值为 0.96 µM。它能够减少突变心肌蛋白和野生型心肌蛋白在细胞中的错误折叠水平，并促进毒性心肌素的清除，从而降低心肌毒性。

HM03 trihydrochloride is a potent and selective inhibitor of HSPA5, also known as Bip or Grp78. It exhibits anticancer activity.

MAO A/HSP90-IN-1 (4-b) 是一种针对MAO A和HSP90的双重抑制剂，展现在恶性胶质瘤GL26细胞上的IC50为1.77 μM，针对HSP90α的IC50为0.019 μM。该化合物能够通过抑制MAO A活性和HSP90结合，以及降低HER2和phospho-Akt表达，进而抗击恶性胶质瘤（GMB）。同时，MAO A/HSP90-IN-1 (4-b)可减少PD-L1的表达，从而降低T细胞活化的抑制，有望用来抑制肿瘤的免疫逃逸。该化合物适用于脑肿瘤相关疾病研究。

A group of tetratricopeptide repeat (TPR)-containing proteins has been shown to interact with the C-terminal domain of the 70 kDa heat-shock cognate protein (hsc70). In the present study, the effect of the TPR-containing proteins, including the C-terminus

SW02 是一种有效的 Hsp70 的 ATPase 活性激活剂 (EC50: 150 μM)。SW02 能够积累总 tau 和磷酸化 tau (pTau)。