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DiaPep277
目录号:SY-109634
DiaPep277为源自HSP60第437-460位点的24个氨基酸组成的多肽,能够抑制NOD小鼠β-细胞破坏进展,并在糖尿病动物模型中对T细胞表现出免疫调节功能。
¥862.00
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Bimoclomol
目录号:SY-109635
Bimoclomol is a heat shock protein co-inducer used for the research of cardiovascular diseases.
¥2058.00
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Specioside
目录号:SY-109636
Specioside是一种天然的环烯醚萜苷,在SPR实验中对重组Hsp90α具有结合活性(Kd=0.026 µM)。
询价
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Calyxin H
目录号:SY-109637
Calyxin H at 1uM can increase the expression of heat shock factor 1 (HSF1), it has a possible application as a heat shock protein (HSP) inducer.
¥1840.00
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YM-1
目录号:SY-109638
YM-1是一种有效的变构 HSP70 抑制剂。它通过促进底物蛋白(如 Akt, Raf-1)降解并干扰蛋白质折叠,表现出强效的抗肿瘤和抗病毒活性。
¥1155.00
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Palmitic acid-13C16 sodium
目录号:SY-109639
Palmitic acid-13C16 sodium, a 13C-labeled form of the naturally occurring saturated fatty acid Palmitic acid sodium, is prevalent in animals and plants. This compound can trigger the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells.
¥2415.00
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Palmitic acid-1,2,3,4-13C4
目录号:SY-109640
Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellular proteins, promotes protein-vesicle interactions, and regulates various G protein-coupled receptor functions.1Red blood cell palmitic acid levels are increased in patients with metabolic syndrome compared to patients without metabolic syndrome and are also increased in the plasma of patients with type 2 diabetes compared to individuals without diabetes.3,4 1.Fatima, S., Hu, X., Gong, R.-H., et al.Palmitic acid is an intracellular signaling molecule involved in disease developmentCell. Mol. Life
¥1035.00
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Palmitic acid-d1
目录号:SY-109641
Palmitic acid-d1 是 Palmitic acid 氘代物。Palmitic acid 为动物和植物中常见的长链饱和脂肪酸。它能够诱导小鼠颗粒细胞中葡萄糖调节蛋白 78 (GRP78) 和 CCAAT/增强子结合蛋白同源蛋白 (CHOP) 的表达。
¥529.00
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Icapamespib HCl
目录号:SY-109642
Icapamespib, also known as PU-HZ 151, is a heat shock protein 90 (HSP90) inhibitor. PU-HZ151 showed EC50 of 5 nM in the FP assay as compared to 11 nM for PU-H71 and a logD of 2.37 as compared to 1.21 for PU-H71. PU-HZ151 and radiolabeled PU-HZ151 showed selectivity for epichaperomes over the individual chaperome members. Icapamespib demonstrated the ability to productively engage the target in cells, mice, and humans.
¥1610.00
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