2-Tetralone (Beta-Tetralone) 是一种促凋亡 (apoptosis) 剂。2-Tetralone 靶向 MDM2 E3 泛素激酶和 Bcl-w 抗凋亡蛋白，并具有抗癌活性。

Flucofuron 对两种福氏耐格里阿米巴菌株 (N. fowleri strains) ATCC 30808 和 ATCC 30215 滋养体的 IC50 值为 2.58 和 2.47 μM，甚至对耐药的包囊阶段也有抑制活性 (IC50 值为 0.88 μM)。Flucofuron 可诱导细胞凋亡 (apoptosis)。Flucofuron 可用于感染和炎症相关研究，如原发性阿米巴脑膜脑炎 (PAM)。

Methyl pyruvate 是丙酮酸的甲基酯衍生物。Methyl pyruvate 诱导胰岛素释放和膜去极化。Methyl pyruvate 通过提升 ATP 的合成挽救了 σ1RE102Q 过表达引起的蛋白酶体损伤和 TdP-43 核外定位。Methyl pyruvate 选择性地保护正常肺成纤维细胞免受 Irinotecan (HY-16562) 诱导的细胞死亡。Methyl pyruvate 在癌细胞中促进凋亡 (apoptosis) 和坏死，并下调血管生成和细胞周期通路。Methyl pyruvate 是二氢二醇脱氢酶的有效底物。

Comp Ie (MC-(β-Ala)-PABC-(β-D-GlcUA)-amide-PEG1-CH2-CC-885) 为一种新型抗体新降解剂偶联活性分子 (AnDC) 的合成降解剂偶联物。

PAC is a chemical conjugate consisting of an ADCs linker and PROTACs linked to an antibody. When PAC is conjugated to an antibody, it exhibits enhanced degradation of estrogen receptor-alpha (ERα) in comparison to PROTAC alone.

MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan 是抗体偶联活性分子的一部分 (drug-linker conjugate for ADC)，包含 Exatecan 。Exatecan 是一种 DNA 拓扑异构酶 I (Topoisomerase I) 抑制剂 (IC50=2.2 μM)。

Mal-PEG4-VA-PBD is a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), comprising the antitumor antibiotic Pyrrolobenzodiazepine (PBD), connected through Mal-PEG4-VA.

NAMPT inhibitor-linker 2, a drug-linker conjugate for antibody-drug conjugates (ADCs), comprises an NAMPT inhibitor payload and a linker. When combined with an anti-c-Kit monoclonal antibody to form ADC-4, it demonstrates potent efficacy against c-Kit expressing cell lines, including GIST-T1 and NCI-H526, with IC50 values of <7 pM and 40 pM, respectively.

MC-Val-Cit-PAB-MMAF is an antibody-drug conjugate (ADC) component that exhibits antitumor properties through the action of the tubulin inhibitor, monomethyl auristatin F (MMAF), which is connected by a cathepsin-cleavable linker, MC-Val-Cit-PAB.