Tipifarnib S enantiomer ((S)-(-)-R-115777) 是Tipifarnib 的 S 型对映体，它比 Tipifarnib 特性低。其中 Tipifarnib 是farnesyltransferase 高效特异性抑制剂，IC50=0.6 nM。

UGT8-IN-1是一种具有口服活性且可穿越血脑屏障的小分子抑制剂，靶向UGT8(神经酰胺半乳糖转移酶)，通过抑制糖鞘脂合成相关通路，被用于溶酶体储存障碍等神经系统疾病机制研究。

7beta-Methoxyrosmanol inhibited acyl CoA:diacylglycerol acyltransferase (DGAT)1 activity, with the IC50 values ranging from 39.5 ± 0.6 to 144.2 ± 3.1 μM.

AGN 192870 是一种有效的维甲酸受体（RAR） 拮抗剂，，对 RARα、RARβ 和 RARγ 亲和力很高。AGN 192870 可用于研究细胞生长停滞，分化和凋亡。

ROS-IN-1是线粒体 ROS 抑制剂，可用于减轻氧化应激或抑制活性氧 (ROS) 的产生。

3-Nitrocoumarin (3-nitrochromen-2-one) (3-NC) 是一个有效的、磷脂酶 C-γ (PLC-γ) 的选择性抑制剂。

Aramchol (C20-FABAC) 是一种胆酸和花生酸的结合物，能够降低硬脂酰辅酶 A 去饱和酶 1 (SCD1) 的活性。它具有用于非酒精性脂肪性肝病 (NAFLD) 和非酒精性脂肪性肝炎 (NASH) 的潜能。

7β,27-dihydroxy Cholesterol is an oxysterol and agonist of retinoic acid receptor-related orphan receptor γ (RORγ) and RORγt. [1] It activates RORγ- or RORγt-dependent signaling with EC50 values of 691 and 1,045 nM, respectively, in reporter assays using HEK293T cells expressing the recombinant human receptors. 7β,27-dihydroxy Cholesterol is selective for RORγ and RORγt over a panel of eight additional nuclear receptors at 30 µM. It increases IL-17A production in Th17-polarized isolated human na ve CD4+ T cells when used at a concentration of 300 nM. 7β,27-dihydroxy Cholesterol (60 mg/kg) increases IL-17A production in isolated mouse γδ T cells stimulated with 12-myristate 13-acetate and ionomycin .

(+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP . (+)-D-threo-PDMP is an inhibitor of glucosylceramide synthase. It inhibits glucosylceramide synthase by 50% when used at a concentration of 5 μM in an enzyme assay. (+)-D-threo-PDMP is the active component of racemic DL-threo-PDMP .