11-Oxoisomogroside V 是从罗汉果(Siraitia grosvenorii)中分离得到的三萜类糖苷化合物，具有抗氧化和抗炎活性。11-Oxoisomogroside V 可激活 PGC-1α 的转录活性。11-Oxoisomogroside V 可提高荧光素酶活性。

NPD10084 是一种靶向丙酮酸激酶 M2 亚型（PKM2）的抑制剂。NPD10084 通过作用于 PKM2 的非糖酵解信号功能，干扰 PKM2 与 β-catenin 或 STAT3 之间的蛋白-蛋白相互作用来抑制下游信号传导，从而对多种结直肠癌细胞系表现出抗增殖活性（体外 IC₅₀范围为 0.8–1.9 μM）。

4-Nitrophenyl phenylphosphonate is a substrate for 5'-nucleotide phosphodiesterases. It is a more preferable substrate to 5'-nucleotide phosphodiesterases than naturally occurring nucleotides or bis(4-nitrophenyl) phosphate because of its stability, ease of synthesis, and higher rate of hydrolysis under saturating conditions.

Alkannin 是一种有效且特异性的肿瘤型丙酮酸激酶-M2 (PKM2) 抑制剂，不抑制 PKM1 和丙酮酸激酶-L (PKL)。Alkannin 是一种潜在的抗癌剂。

ENPP1 inhibitor 43 is a novel small molecule for cancer immunotherapy.

ITI-214 free base is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM).

L-6355 is an agent of bioactive chemicals.

Tetomilast (OPC-6535) is a phosphodiesterase-4 (PDE4) inhibitor, potentially effective in treating inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD).

Rp-cAMPS TEA salt is a cAMP-dependent protein kinase (PKA) activator.