DM3

目录号：SY-100640

DM3 (Maytansinoid DM3) is a maytansine mimic with disulfide or thiol groups, acting as a tubulin inhibitor and serving as the cytotoxic component in antibody-drug conjugates (ADCs).

¥2189.00

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Fmoc-MMAE

目录号：SY-100639

Fmoc-MMAE, a protective group-conjugated variant of monomethyl auristatin E (MMAE), serves as a powerful inhibitor of tubulin. It finds application in the synthesis of antibody-drug conjugates (ADC).

¥682.00

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Tubulysin M

目录号：SY-100638

Tubulysin M is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin M is a cytotoxic activity tubulysin that inhibits tubulin polymerization and leads to ce

¥12765.00

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T01-1

目录号：SY-100637

T01-1 是一种抗癌剂 (喜树碱衍生物)，具有较好的抗肿瘤细胞增殖活性。

¥1932.00

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SJG-136

目录号：SY-100636

SJG-136 is a DNA cross-linking agent (XL50: 45 nM for pBR322 DNA).

¥2576.00

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β-Amanitin

目录号：SY-100635

β-Amanitin, a cyclic peptide toxin found in the poisonous Amanita phalloides mushroom, inhibits eukaryotic RNA polymerase II and III, thereby disrupting protein synthesis.

¥6773.00

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Tomaymycin DM

目录号：SY-100634

Tomaymycin DM，一种Tomaymycin衍生的DNA烷化剂，作为肿瘤靶向抗体偶联活性分子(ADCs)有效载荷，是PBD单体。

¥1805.00

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NH2-methylpropanamide-Exatecan TFA

目录号：SY-100633

NH2-methylpropanamide-Exatecan (TFA) 为对异丁酰胺进行修饰的Exatecan，属于ADC毒素（ADC Cytotoxin），应用于ADC合成中。该化合物作为DNA拓扑异构酶I（topoisomerase I）抑制剂，具有2.2 μM（0.975 μg/mL）的IC50，适用于癌症研究。

¥5060.00

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DC0-NH2

目录号：SY-100632

The cytotoxicity of DC0-NH2 is 1000 times that of commonly used anti-cancer drugs (such as doxorubicin). It is the effect part of ADC. It is a simplified simulation of DC1 and has better stability. DC0-NH2 can bind to the small groove of DNA, and then ade

¥2530.00

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