Tubulysin A

目录号：SY-100631

Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, and anti-angiogenic.

¥4312.00

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Exatecan Intermediate 5

目录号：SY-100630

Exatecan Intermediate 5 作为Exatecan的中间体,其应用广泛.Exatecan (DX-8951),一个有效的DNA拓扑异构酶I (topoisomerase I) 抑制剂,具IC50为2.2 μM (0.975 μg/mL),主要用于癌症治疗研究.此外,Exatecan Intermediate 5 还关键于抗体-药物偶联物 (Antibody-Drug Conjugates (ADCs)) 的合成过程.

¥7590.00

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(R)-Exatecan Intermediate 1

目录号：SY-100629

(R)-Exatecan Intermediate 1 为 Exatecan Intermediate 1 的异构体,属于Exatecan的中间体之一.Exatecan (compound 6) 作为一种喜树碱类的抗癌药物,其机制是通过与DNA相互作用,进而干扰肿瘤细胞的增殖与分裂,抑制癌症生长.该药物主要用于研究卵巢癌、肺癌和乳腺癌等多种癌症.

¥425.00

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Rebeccamycin

目录号：SY-100628

Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and topoisomerase II.

¥17250.00

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γ-Amanitin

目录号：SY-100627

γ-Amanitin an ADC cytotoxin and isolated from the mushroom. γ-Amanitin inhibits RNA polymerase II and disrupts synthesis of mRNA. γ-Amanitin shows similar effects to α-Amanitin and β-Amanitin.

¥10350.00

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Aminohexylgeldanamycin

目录号：SY-100626

Aminohexylgeldanamycin (AHGDM), a derivative of Geldanamycin, is a highly effective inhibitor of HSP90. It exhibits considerable antiangiogenic and antitumor properties[1].

¥1564.00

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MMAF Hydrochloride

目录号：SY-100625

MMAF Hydrochloride is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF Hydrochloride is an effective tubulin polymerization inhibitor and is used as an antitumor compound.

¥460.00

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Duocarmycin DM free base

目录号：SY-100624

Duocarmycin is a DNA minor groove binding alkylating agent and explored as drug–antibody conjugates (ADCs) . Duocarmycin is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity.

¥3335.00

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Exatecan Intermediate 7

目录号：SY-100623

Exatecan Intermediate 7 为Exatecan的中间体.Exatecan (DX-8951) 作为一种抑制DNA拓扑异构酶I (topoisomerase I) 的化合物,具有IC50值2.2 μM (0.975 μg/mL),主要用于癌症研究.此中间体还可用于合成抗体-药物偶联物 (Antibody-Drug Conjugates (ADCs)).

¥1840.00

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