Hemiasterlin

目录号：SY-100613

Hemiasterlin is a cytotoxic peptide that acts by inducing mitotic arrest and abnormal spindle formation.

¥3450.00

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Duocarmycin A

目录号：SY-100612

Duocarmycin A, an antitumor antibiotic, is a DNA alkylator and efficiently alkylates adenine N3 at the 3′ end of AT-rich sequences in the DNA. Duocarmycin A, as a chemotherapeutic agent, results in HLC-2 cells typically apoptotic changes.

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DGN462

目录号：SY-100611

DGN462 is an effective DNA alkylating agent with anti-tumor activity, as in acute myeloid leukemia (AML). DGN462 can be used as a cytotoxic component of antibody-drug conjugates (ADCs).

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Glucocorticoid receptor agonist-2

目录号：SY-100610

Glucocorticoid receptoragonist-2 (compound 21) 作为一种糖皮质激素受体激动剂，具有 6.6 nM 的 IC50 值，主要用于抗炎 ADC 分子的合成。同时，它也是 ABBV-3373 的活性对照物。

¥2618.00

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S-methyl DM1

目录号：SY-100609

S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.

¥1925.00

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PNU-159682 carboxylic acid

目录号：SY-100608

PNU-159682 carboxylic acid is a potent ADCs cytotoxin,PNU-159682 carboxylic acid has protein fold and diverse functions.

¥7199.00

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Gly-Gly-Phe-Gly-NH-O-CO-Exatecan

目录号：SY-100607

Gly-Gly-Phe-Gly-NH-O-CO-Exatecan 属于 ADC 毒素类化合物.

¥999.00

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Exatecan Intermediate 4

目录号：SY-100606

Exatecan Intermediate 4 (compound B),作为Exatecan (DX-8951)的中间体,属于抗癌类化合物.Exatecan是一种喜树碱类似物,通过与DNA相互作用,抑制肿瘤细胞的增殖与分裂,从而阻断肿瘤的生长.该药物主要用于研究卵巢癌、肺癌和乳腺癌等多种癌症.

¥1782.00

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Benzyl DC-81

目录号：SY-100605

Benzyl DC-81 (Compound 6a) 是一种抗癌化合物，展现对A375和MCF-7细胞线具有显著的抗增殖作用。

¥782.00

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