GB1874是一种靶向β-cat-TCF4 PPI的Wnt通路的抑制剂，影响wnt依赖性结直肠癌(CRC)细胞的增殖和干细胞性，在体内抑制HCT116肿瘤异种移植物的生长。

AS1134900 是一种高选择性的、非竞争性的、变构的 NADP+依赖的苹果酸酶 1 (ME1) 抑制剂。

Prodigiosin hydrochloride, a red pigment, is a bioactive secondary metabolite produced by bacteria. It exhibits potent proapoptotic activity and functions as an inhibitor of the Wnt/β-catenin pathway. Additionally, this compound possesses antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties.

2-Hydroxycinnamaldehyde is a natural product.

2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflammation and oxidative stress for preservation of BBB integrity. 2-Methoxystypandrone concomitant

OM-153 是 tankyrase 的有效抑制剂，能够作用于 tankyrase 1 (IC50: 13 nM) 和 tankyrase 2 (IC50: 2 nM)，且对 COLO 320DM 中的 WNT/β-连环蛋白信号传导和增殖具有抑制作用。

NC043 is an inhibitor of Wnt/β-catenin signaling, it forms a covalent bond with the Cys-516 residue of CARF.

ZW4864 is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor. ZW4864 inhibits β catenin/BCL9 PPI with a K i value of 0.76 μM and an IC 50 value of 0.87 μM.

β-catenin peptide,(βCATp) is a naturally occurring self-peptide presented by Kb that very efficiently mediates positive selection of the OT-I thymocytes.