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UU-T01
目录号:SY-110267
UU-T01 是 β-Catenin/T-cell factor 4 蛋白互作 (β-catenin/Tcf PPI) 的选择性抑制剂,Ki 值为 3.14 µM。UU-T01 与β-catenin 直接结合,KD 值为 0.531 µM。
¥1725.00
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16,16-Dimethyl prostaglandin E2
目录号:SY-110268
16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It can act through EP2/EP4 and has an interaction with the Wnt pathway.
¥3036.00
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A3334
目录号:SY-110269
A3051, is a robust and orally active inhibitor of CXXC5-DVL with an IC 50 of 63.06 nM. Its applications include research into phenotypes associated with obesity, diabetes, and NASH that are induced by high fat diet (HFD) and methionine-choline deficient diet (MCD).
¥1828.00
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TWS-119
目录号:SY-110270
TWS-119是一种强效 GSK-3β 抑制剂,可激活 Wnt/β-catenin 信号通路。它能诱导神经元分化,增强 T 细胞抗肿瘤活性,并在缺血性卒中模型中保护血脑屏障。
¥920.00
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GNF-1331
目录号:SY-110271
GNF-1331 is a potent, selective, and orally bioavailable porcupine inhibitor (IC50 = 12 nM). Blocking abnormal Wnt signaling is an attractive treatment for a variety of cancers.
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FZD7 antagonist 1
目录号:SY-110272
FZD7 antagonist 1 (peptide 34), a dFz7-21 analogue, inhibits wnt3a with an IC50 of 9.2 nM and blocks TcdB−FZD interaction by targeting FZD receptors [1].
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PTK7/β-catenin-IN-6
目录号:SY-110273
PTK7/β-catenin-IN-6 (Compound 03653) 作为一类抑制PTK7/β-catenin相互作用的化合物,能有效地抑制Wnt信号通路,对结直肠癌 (CRC) 具有抗癌效果。
¥4278.00
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β-catenin-IN-6
目录号:SY-110274
β-catenin-IN-6是一种针对Wnt/β-catenin(典型的wingless相关整合位点)通路的抑制剂,能够抑制人类结直肠癌细胞的增殖,并在β-catenin/RK3E小鼠模型上展现出效果。
¥4257.00
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8-Prenylkaempferol
目录号:SY-110275
8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction, it may be an anti-inflammatory agent for suppressing influenza A virus-induced RANTES production acts by blocking PI3K-mediated transcriptional activation of NF-κB and
¥5814.00
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