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Azido-PEG6-amine
目录号:SY-100928
Azido-PEG6-amine is a polyethylene glycol (PEG)-based linker compound commonly employed in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1]. Additionally, it serves as a non-cleavable 6-unit PEG linker in the synthesis of antibody-drug conjugates (ADCs)[2].
¥506.00
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Ac-EEVC-OH
目录号:SY-100927
Ac-EEVC-OH 是一种用于 ADC 分子合成的连接子。
¥1150.00
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PDP-Pfp
目录号:SY-100926
PDP-Pfp is a reducible ADC linker primarily utilized for targeting agents aimed at the extracellular loop 1 (ECL1) of TM4SF1, a member of the transmembrane 4 L6 family, as supported by reference [1].
¥2116.00
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DBCO-PEG4-Val-Cit-PAB-PNP
目录号:SY-100925
DBCO-PEG4-Val-Cit-PAB-PNP 是一种可裂解的 ADC 连接子,其中 Val-Cit 可以被 Cathepsin B 特异性裂解,而 PNP 可以被含胺的有效载荷取代。DBCO 能与叠氮化物分子通过点击化学反应结合。
¥984.00
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Propargyl-PEG4-Br
目录号:SY-100924
Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
¥310.00
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Boc-Gly-Sar-OH
目录号:SY-100923
Boc-Gly-Sar-OH为一类可裂解的ADC连接子.
¥515.00
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γ-Glu-Val-Gly
目录号:SY-100922
γ-Glu-Val-Gly 是可裂解的 ADC 连接子.
¥299.00
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Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH
目录号:SY-100921
Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH 作为合成ADC linker的中间体,具备关键作用。其中,Benzyl 2-cyclopropyl-2-hydroxyacetate 构成的linker能够与Exatecan进行偶联,并可与抗体(如 hu2F7)进行结合。
¥1127.00
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Val-Lys(Boc)-PAB
目录号:SY-100920
Val-Lys(Boc)-PAB, an ADC linker, facilitates the synthesis of camptothecin peptide conjugates as antitumor agents and serves as a non-linear self-immolative linker to lessen the hydrophobicity of antibody-drug conjugates in cancer therapy.
¥1104.00
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