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all-trans-5,6-epoxy Retinoic Acid
目录号:SY-128822
all-trans-5,6-epoxy Retinoic Acid 可用于生命科学领域的相关研究。其产品编号为 T36382,CAS号为 13100-69-1。
¥2404.00
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D-threo-PPMP hydrochloride
目录号:SY-128936
D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor.1,2It is the active enanantiomer and enzymatic inhibitory component of the racemic DL-threo-PPMP . In MDCK kidney epithelial cells, D-threo-PPMP induces a 70% reduction in cell growthin vitroat 20 μM and significantly inhibits DNA synthesis at 3 μM.3[Matreya, LLC. Catalog No. 1865] 1.Shen, W., Henry, A.G., Paumier, K.L., et al.Inhibition of glucosylceramide synthase stimulates autophagy flux in neuronsJ. Neurochem.129(5)884-894(2014) 2.Lee, L., Abe, A., and Shayman, J.A.Improved inhibitors of glucosylceramide synthaseJ. Biol. Chem.274(21)14662-14669(1999) 3.Abe, A., Inokuchi, J.-i., Jimbo, M., et al.Improved inhibitors of glucosylceramide synthaseJ. Biochem.111(2)191-196(1992)
¥4025.00
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Xanthine oxidoreductase-IN-4
目录号:SY-129026
Xanthine oxidoreductase-IN-4 是一种具有有口服活性黄嘌呤氧化还原酶 (XOR) 抑制剂,对 XOR 具有抑制作用,IC50 值为 29.3 nM。Xanthine oxidoreductase-IN-4 可用于研究高尿酸血症。
¥667.00
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Cobalt protoporphyrin IX
目录号:SY-128685
Cobalt protoporphyrin IX 作为一种特异性的血红素加氧酶-1 (HO-1) 诱导剂,表现出对甲型流感病毒 (IAV) 的广谱抗病毒活性。
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BLV
目录号:SY-128739
BLV 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2484,CAS号为 146905-24-0。
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Viaminate
目录号:SY-128820
Viaminate为维甲酸衍生物,主要用于处理严重痤疮及其它角质化相关疾病。
¥207.00
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D-threo-PPMP
目录号:SY-128925
D-threo-PPMP, a powerful glucosylceramide (GlcCer) synthase inhibitor, effectively impedes karyokinesis and decreases cyst formation.
¥2875.00
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(1S)-Calcitriol
目录号:SY-129006
(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion[1]. 3‐epi‐Calcitroic acid is an end product of (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3; 3‐epi‐1a,25(OH)2D3) metabolism by rat CYP24A1[1]. [1]. Steve Y Rhieu, et al. Metabolic stability of 3-epi-1α,25-dihydroxyvitamin D3 over 1 α 25-dihydroxyvitamin D3: metabolism and molecular docking studies using rat CYP24A1. J Cell Biochem. 2013 Oct;114(10):2293-305.
¥4620.00
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Varespladib
目录号:SY-128370
Varespladib (LY315920) 是选择性group IIA, secretory phospholipase A2(sPLA2)抑制剂,其IC50=9 nM。它对大鼠,兔,豚鼠和人等各种物种血清的sPLA2活性具有明显的抑制作用,IC50分别为 8.1 nM,5.0 nM,3.2 nM 和 6.2 nM。
¥1078.00
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