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PB038
目录号:SY-101352
PB038为一种ADC药物,由可降解的PEG linker及毒素分子依喜替康(Exatecan)构成的偶联物。
¥3450.00
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SG3199-Val-Ala-PAB
目录号:SY-101353
SG3199-Val-Ala-PAB为Tesirine合成中间体,该物质作为用于抗体偶联活性分子(ADC)的活性分子-linker连接物,适用于多种癌症研究。
¥3450.00
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Deruxtecan analog 2
目录号:SY-101354
Deruxtecananalog 2(示例9 P3)是一种含活性分子-linker的Deruxtecan类似物,由Camptothecin(一种对多种癌症如结直肠癌、乳腺癌、肺癌和卵巢癌具有抗肿瘤活性的Topo I抑制剂)和linker组成,主要用于开发针对EGFR2的抗体药物偶联物(ADC)活性分子。
¥2058.00
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NAMPT inhibitor-linker 1
目录号:SY-101355
NAMPT inhibitor-linker 1, a drug-linker conjugate for ADC, integrates an NAMPT inhibitor (as a payload) with a linker. In the formulation of ADC-3, it pairs with an anti-c-Kit monoclonal antibody, demonstrating strong efficacy against c-Kit expressing cell lines, specifically GIST-T1 and NCI-H526, where it exhibits IC50 values of <3 pM and 9 pM, respectively.
¥3220.00
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MC-Val-Cit-PAB-duocarmycin chloride
目录号:SY-101356
MC-Val-Cit-PAB-duocarmycin is an antibody-drug conjugate (ADC) linker that combines duocarmycin, a potent DNA minor groove-binding alkylating agent, with an antitumor drug through the MC-Val-Cit-PAB linker, exhibiting significant antitumor activity.
¥4830.00
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sulfo-SPDB-DM4
目录号:SY-101357
Sulfo-SPDB-DM4 is a drug-linker conjugate designed for antibody-drug conjugates (ADCs) that employs the maytansine-based payload (DM4, an antitubulin agent) connected through the sulfo-SPDB linker.
¥23805.00
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