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POSH-IN-2
目录号:SY-109463
POSH-IN-2 (MIDI) 作为一种DRP1抑制剂,能有效抑制细胞应激和遗传性线粒体损伤引起的线粒体分裂。该化合物通过与DRP1-C367共价结合,阻断DRP1与其多个受体的交互作用,从而实现其线粒体分裂抑制功能。
¥3450.00
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Meclofenamic acid
目录号:SY-109523
Meclofenamic acid (Meclofenamate) 是一种非特异性 gap-junction 阻滞剂和特异性脂肪量和肥胖相关 (FTO) 酶抑制剂。 Meclofenamic acid 具有抗炎活性。
¥943.00
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BPC 157 (X acetate)
目录号:SY-109495
Body Protection Compound 157 (BPC 157) is a pentadecapeptide derived from BPC, identified in gastric juice, exhibiting diverse biological activities. At 2 µg/ml, BPC 157 enhances primary rat tendon fibroblast cell migration and F-actin formation. Furthermore, doses of 0.01 and 10 µg/kg, intraperitoneally (i.p.), mitigate paw swelling, bone erosion, and mononuclear cell infiltration in the joints of rats with rheumatoid arthritis induced by complete Freund's adjuvant (CFA). It also diminishes gastric ulcer size in rats caused by indomethacin, aspirin, or diclofenac at these doses. Additionally, BPC 157 reduces catalepsy duration and tremor severity in a mouse model of Parkinson's disease triggered by MPTP.
¥1092.00
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GSK215
目录号:SY-109480
GSK215是一种强效和选择性的粘着斑激酶(FAK)PROTAC 降解剂(pDC50=8.4)。GSK215包含 FAK 抑制剂 VS-4718和 VHL E3连接酶的粘合剂。GSK215可以诱导 FAK 的快速和长期降解。
¥957.00
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hRIO2 kinase ligand-1
目录号:SY-110009
hRIO2 kinase ligand-1 是一种有效的 hRIO2 激酶的配体(Kd:520 nM)。
¥1208.00
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Aurothiomalate sodium
目录号:SY-109995
Aurothiomalate sodium (Miochrysin) 是一种选择性的致癌 PKCι信号传导抑制剂,可抑制肿瘤细胞增殖。它是一种硫氧还蛋白还原酶 (TrxR) 抑制剂,也是一种抗风湿剂。
¥251.00
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