GPR88-IN-1为GPR88抑制剂，适用于中枢性疾病研究。

BI-2081是一种GPR40 (FFAR1)部分激动剂，具有EC50值为4 nM。该化合物能诱导葡萄糖依赖性胰岛素释放，并降低血浆中葡萄糖含量，适用于研究代谢疾病，尤其是2型糖尿病。

GSK1104252A is a potent and selective agonist of GPR119.

GPR35 agonist 1 is a highly effective and specific GPR35/CXCR8 agonist (EC50: 5.8 nM).

GPR52受体调制剂1（程序1）是一种有潜力用于神经精神疾病研究的GPR52受体调节剂。

ALB-127158(a) 是一种有效的选择性黑色素浓缩激素 1 (MCH1) 受体拮抗剂，可能是炎症性肠病 (IBD) 的潜在治疗方法

Ac-hMCH(6-16)-NH2 shows non-selective agonist activity towards both MCH-1R and MCH-2R, which are human MCH receptors in the brain. The compound effectively binds to and activates these receptors, with IC 50 values of 0.16 nM and 2.7 nM for MCH-1R and MCH-2R, respectively.

Commendamide is a natural bacterial product that was discovered in a screen for commensal bacteria effector genes (Cbegs). Cbeg12 is a bacterial effector gene that encodes for its production. Commendamide is structurally similar to long-chain N-acyl-amides, which commonly signal, in mammals, through G protein-coupled receptors. Commendamide activates GPR132 (also known as G2A) with an EC50 value of 11.8 μM.

BMS-986118 is a full agonist of GPR40, is a G-protein-coupled receptor expressed primarily in pancreatic islets and intestinal L-cells that has been a target of significant recent therapeutic interest for type II diabetes. Activation of GPR40 by partial a